organic circulation and persistence of foot – and – mouth disease virus type o in guinea pig

Organic Circulation and persistence of Foot – and – Mouth disease virus type O in guinea pig

Since, the most susceptible laboratory animal to Foot–and–Mouth disease virus (FMDV) is guinea pig, and then one milliliter of FMDV type (O) concentrations of 106-106.5 TCID50was inoculated intradermally (ID) to 10 plantar surface of guinea pig (right side). Guinea pig adapted virus has been prepared after generalization phase, and then one milliliter of virus was inoculated intradermally to 30...

Evaluation of cytokine mRNA expression in vaccinated guinea pigs with foot-and-mouth disease type O inactivated vaccine

Foot-and-mouth disease (FMD) is a severely contagious viral disease that mainly affects cloven-hoofedlivestock and wildlife. This study quantifies the cytokines mRNA expression of vaccinated guinea pigs withFMD type O inactivated vaccine. Blood samples were collected from eight guinea pigs at 7 and 28 days after thefirst vaccination. Extracted mRNAs were reverse-transcribed into cDNA and analyz...

Molecular Cloning of VPI gene of Foot-and-Mouth Disease Virus Type 01/Iran

amino acid diversity of antigenic sites of iranian type o foot-and-mouth disease virus

foot-and-mouth disease (fmd) is a major cause of endemic outbreaks in livestock in iran. in this study, clinical field samples of foot-and-mouth disease virus were collected from an outbreak in khorasan razavi province during april and august of 2010, and subjected to indirect sandwich elisa and rt-pcr. the viral serotype circulating during the period was confirmed to be type o. the virus was t...

Lyophilizing Foot-and Mouth Disease Virus at Low Drying Temperature

The situation of foot and mouth disease virus types and subtypes in Iran in 1980-1983